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Cardiotoxicity, which can present as fulminant myocarditis, is one of the rare but catastrophic irAEs

Also, with the increase time of reaction to 72 h, the color of the reaction changed to dark brown

This is where some background information may be provided, the structure of the AOP is described, and the KEs and KERs are listed

And the combined application of glutamine metabolism inhibitors with immune checkpoint inhibitorss has demonstrated enhanced efficacy in inhibiting cancer development

The aims of these trials is to achieve fat-selective weight loss, improved body composition and end-organ protection via a triple mechanism effect in people living with obesity [114]